Article #12 from the complete research library
The Chemistry of HOCl and Inflammation
Biological reactivity and biomarkers of the neutrophil oxidant, hypochlorous acid.
Authors: Christine C Winterbourn
Journal: Toxicology (2002)
Abstract in Hebrew:
Free radicals or reactive oxygen species are considered contributors to the pathology of many diseases. These include inflammatory conditions, where neutrophils accumulate in large numbers and are stimulated to produce superoxide and other reactive oxidants. Hypochlorous acid (HOCl), produced by the accelerated oxidation of chloride by myeloperoxidase using hydrogen peroxide, is the main strong oxidant generated.
