Article #11 from the complete research library
Oxidative Pathways in the Immune System
Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly.
Authors: J S Beckman, W H Koppenol
Journal: The American Journal of Physiology (1996)
Abstract in Hebrew:
Unlike most intercellular mediators, nitric oxide diffuses rapidly and isotropically through most tissues with minimal reaction, but it cannot be transported through blood vessels due to rapid breakdown by oxyhemoglobin. The rapid diffusion of nitric oxide between cells allows it to locally integrate vascular responses to turbulence, regulate synaptic plasticity in































